Makassar Pharmaceutical Science Journal (MPSJ)

A LITERATUR REVIEW : VCO SEBAGAI ANTI KETOMBE

2025-03-17T03:33:43+00:00

Hair serum has become a popular care product to maintain healthy and beautiful hair. Pure coconut oil (VCO) is known to have great potential in hair care because of its natural nutritional content. One of the main ingredients in VCO is lauric acid. The high lauric acid content in this vco has antimicrobial and antifungal properties which are effective against dandruff. Dandruff is flakes of (dead) scalp that peel off. The epithelium that makes up the scalp is a stratified squamous epithelium that continuously grows, thereby pushing the old epithelium above it to the surface where it will then die and eventually peel off (corneocytes). Where the use of VCO can prevent dandruff. However, VCO is not applied directly to the scalp, therefore a serum preparation is made first. The advantage of serum compared to other preparations is that it is highly concentrated so it is absorbed more quickly into the skin. Based on the many health problems that often occur on the scalp and hair, the aim of the research is to conduct a literature review on what ingredients are contained in VCO so that it can be made into a hair serum preparation. The method used in reviewing this article is to carry out online search process using several search engines such as Google Scholar, Scopus, and Schoolar with the keywords: Virgin Coconut Oil, Dandruff, Emulgel, Serum. The sources obtained are international and national journals. Articles were selected based on inclusion criteria, namely those published in the last 10 years with suitability for writing keywords, relevance of writing results and discussion.

UJI AKTIVITAS ANTIOKSIDAN EKSTRAK ETANOL DAUN KENIKIR (Cosmos caudatus Kunth) DENGAN METODE FERRIC REDUCING ANTIOXIDANT POWER

2025-03-17T03:34:48+00:00

Antioxidants are defined as inhibitors that work with the oxidation process, even at relatively small concentrations. Antioxidants are substances that can delay, slow down and prevent the oxidation process. Kenikir leaves contain flavonoid compounds, polyphenols, saponins, tannins, alkaloids and essential oils and also contain bioactive compounds such as ascorbic acid, quercetin, chlorogenic acid and polyphenolic compounds which function as antioxidants. The aim of this research was to determine the antioxidant activity test of the ethanol extract of Kenikir leaves using the FRAP (Ferric Reducing Antioxidant Power) method. The Kenikir leaf extraction method uses the maceration method with 96% ethanol solvent to obtain Kenikir leaf ethanol extract. The ethanol extract of Kenikir leaves was reacted with several FRAP reagents and then measured using a UV-Vis spectrophotometer at a maximum wavelength of 720 nm. Quercetin as a comparison with the quercetin test results obtained a linearity equation of y = 0.0117x + 0.4212 with a correlation coefficient value of r = 0.9986. The results showed that the ethanol extract of Kenikir leaves had an antioxidant activity of 12.7464 mgQE/g extract.

POTENSI AKTIVITAS ANTIBAKTERI FUNGI ENDOFIT DAUN PARANG ROMANG (Boehmeria virgata) (G.Forst.) Guill TERHADAP BAKTERI UJI MICROCOCCUS LUTEUS DAN BACILLUS SUBTILIS SECARA KLT-BIOAUTOGRAFI

2025-03-17T06:42:58+00:00

Parang romang (Boehmeria virgata (G.Forst) Guill) is a plant used to treat various infectious diseases, one of which is the digestive tract. Antibacterials are compounds that can inhibit or kill bacteria that cause infection. Endophytic fungi produce bioactive compounds in the form of antioxidants, anticancer, antiviral, antifungal and so on. This research uses the TLC-Bioatography method. The research started with the isolation of endophytic fungi and antagonist tests, which obtained active isolates against the test bacteria Micrococcus luteus and Bacillus subtilis, namely IFBV-6. Then this isolate was fermented and continued with testing using the TLC-Bioautography method. The resulting fermentate was dissolved in chloroform:methanol (5:1) solvent. Test results from TLC-Bioautography of IFBV-6 fermentate showed Rf values of 0.9, 0.81 and 0.58. In the case of Micrococcus luteus and bacillus subtilis bacteria, good Rf values from TLC show that there is quite good separation, ranging from 0.2-0.8, indicating clear antibacterial activity. In this test, each fermentation code has the same Rf value and number of spots. The results of identifying the chemical components of endophytic fungal isolates from parang romang leaves of Boehmeria virgata (G.Forst) Guill) gave positive results using alkaloid and saponin spotting.

Antioxidant Activity ANTIOXIDANT ACTIVITY OF ETHANOL EXTRACT OF RED BAJAKAH KALALAWIT ROOTS (Uncaria gambir Roxb) USING THE FRAP METHOD

2025-03-17T06:43:29+00:00

Akar bajakah kalalawit merah (Uncaria gambir Roxb) merupakan salah satu tanaman yang dikenal memiliki kandungan alkaloid, fenol, dan triterpenoid yang digunakan untuk mengobati kanker, tumor, luka, penuaan dini, diabetes, dan antioksidan. Antioksidan adalah suatu senyawa yang memiliki struktur molekul yang dapat memberikan elektron untuk molekul radikal bebas yang tidak stabil tanpa terganggu sama sekali sehingga dapat memutuskan reaksi berantai radikal bebas. Tujuan penelitian ini adalah untuk mengetahui aktivitas antioksidan ekstrak etanol akar bajakah kalalawit merah (Uncaria gambir Roxb) menggunakan metode FRAP, berdasarkan kemampuan sampel mereduksi ion Fe3+ menjadi Fe2+. Hasil pengujian kualitatif menunjukkan bahwa akar bajakah kalalawit merah (Uncaria gambir Roxb) mengandung senyawa alkaloid, flavonoid, fenolik,dan tannin. Hasil pengujian kuantitatif diperoleh nilai rata-rata aktivitas antioksidan ekstrak etanol akar bajakah kalalawit merah (Uncaria gambir Roxb) yaitu sebesar 193,403 mg QE/g ekstrak.

Analysis of Tannin Analysis of Tannin Compounds in Dried and Fresh Turmeric (Curcuma longa L.) Rhizomes using UV – Vis Spectrophotometry

2025-03-18T01:41:55+00:00

Turmeric is a biopharmaceutical plant originating from the Zingiberaceae family, widely distributed in Southeast Asia and Africa. The rhizome of Turmeric (Curcuma longa L.) is the most commonly used part in various applications such as traditional medicine, textile dyes, food, spices, and cosmetics. This study aims to determine the tannin content in turmeric rhizomes (Curcuma longa L.), both in dry and fresh conditions, extracted with 96% ethanol solvent, and measured using UV-Vis spectrophotometry. The results showed that the extracts of both dry and fresh turmeric rhizomes (Curcuma longa L.) contain tannin compounds. Quantitatively, the extracts were measured at a maximum wavelength of 706 nm with gallic acid as a standard, yielding the regression equation y = 0.0898x – 0.037, an r-value of 0.9955, and the average tannin content of dry turmeric rhizome extract being 29.005 mg GAE/g extract and fresh turmeric rhizome extract being 57.046 mg GAE/g extract. This study indicates that fresh turmeric rhizome extract contains higher tannin levels than dry turmeric rhizome extract.