SCREENING TEST ON THE ANTIBACTERIAL ACTIVITY OF THE n-HEXANE FRACTION OF LEMERAH LEAVES (Cymbopogon citrantus) AGAINST BACTERIA CAUSING SKIN INFECTIONS
Abstract
Indonesia as a tropical country has a diversity of biological natural resources. This diversity is very beneficial, especially with the large number of plant species that can be used as medicine. One plant that is believed to be used as medicine is lemongrass which has lush and dense leaves. Lemongrass leaves (Cymbopogon citratus) is one of the medicinal plants and can be used as a kitchen spice. Lemongrass plants are very easy to find in Indonesia and contain alkaloids, saponins, tannins, polyphenols, flavonoids, and essential oils. Saponins and essential oils are the main group of chemicals that can exert activity against microbes. This study aims to conduct a screening test of antibacterial activity of the n-hexan fraction of lemongrass leaves (Cymbopogon citrantus) against bacteria that cause skin infections. This research method was conducted experimentally to test the antibacterial activity of lemongrass leaves by screening test. The results in this study, the n-hexan fraction of lemongrass leaves can inhibit the growth of test bacteria Staphylococcus aureus, Pseudomonas aureginosa, Staphylococcus epidermidis, and Propionibacterium acne. It can be concluded that lemongrass leaves (Cymbopogon citrantus) have antibacterial activity.
References
[2] A. Harly Nurung, T. Naid, dan D. R. Umarella, “AKTIVITAS ANTIBAKTERI EKSTRAK ETANOL DAUN KIRINYUH (Chromolaena odorata (L.) R. M.) SECARA KLT BIOAUTOGRAFI,” 2021.
[3] S. A. F. Kawengian dkk., “Uji daya hambat ekstrak daun serai (Cymbopogon citratus L) terhadap pertumbuhan Streptococcus mutans,” 2017.
[4] T. Nasional dkk., “eISSN 2337-330X eBiomedik,” vol. 9, no. 1, 2021, doi: 10.35790/ebm.9.1.2021.31716.
[5] J. Farmasi Galenika ; Electronic, ) Rahman Razak, dan A. R. Tandah, “Uji Aktivitas Antibakteri Sediaan Gel Ekstrak Daun Sereh (Cymbopogon nardus L. Rendle) terhadap Bakteri Staphylococcus aureus Penyebab Jerawat,” Galenika Journal of Pharmacy), vol. 3, no. 2, hlm. 143–149, 2017, doi: 10.22487/j24428744.2017.v3.i2.8770.
[6] Y. Nuryadin, T. Naid, A. Amaliah Dahlia, K. Seniwati Dali, dan S. Selatan, “Kadar Flavonoid Total Ekstrak Etanol Daun Serai Dapur dan Daun Alang-Alang Menggunakan Spektrofotometri UV-VIS,” Jurnal Kesehatan, vol. 1, no. 4, 2018.
[7] B. Maria, B. Sikawin, P. V. Y. Yamlean, dan S. Sudewi, “FORMULASI SEDIAAN GEL ANTIBAKTERI EKSTRAK ETANOL TANAMAN SEREH (Cymbopogon citratus (DC.) Stapf) DAN UJI AKTIVITAS ANTIBAKTERI (Staphylococcus aureus) SECARA in vitro,” 2018.
[8] P. M. Tambunan, “KARAKTERISASI DAN UJI TOKSISITAS AKUT EKSTRAK ETANOL DAUN SERAI (Cymbopogon citratus) DESA BANDAR KHALIPAH TERHADAP MENCIT JANTAN (Mus musculus),” JURNAL KIMIA SAINTEK DAN PENDIDIKAN, vol. 6, no. 1, hlm. 1–10, Jul 2022, doi: 10.51544/kimia.v6i1.2968.
[9] P. Erlyn, “Efektivitas Antibakteri Fraksi Aktif Serai (Cymbopogon citratus) terhadap Bakteri Streptococcus mutans,” 2016.
[10] N. Afni dan N. Said, “UJI AKTIVITAS ANTIBAKTERI PASTA GIGI EKSTRAK BIJI PINANG (Areca catechu L.) TERHADAP Streptococcus mutans DAN Staphylococcus aureus ANTIBACTERIAL ACTIVITY TEST of TOOTHPASTE OF BETEL NUT (Areca catechu L.) EXTRACT AGAINST Streptococcus mutans AND Staphylococcus aureus.”
[11] N. Wijayati, C. Astutiningsih, dan S. Mulyati, “Biosaintifika 6 (1) (2014) Transformation α-Pinena by Bacteri Pseudomonas aeruginosa ATCC 25923 ,” 2014. [Daring]. Tersedia pada: http://journal.unnes.ac.id/nju/index.php/biosaintifikaTransformasiα-PinenadenganBakteriPseudomonasaeruginosaATCC25923
[12] H. N. Sekeon dkk., “Uji Konsentrasi Hambat Minimum Ekstrak Daun Gedi (Abelmoschus manihot L.) terhadap Pertumbuhan Bakteri Streptococcus Mutans.”
